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Does Ibogaine treatment really work?
A single Ibogaine treatment experience reduces opioid withdrawal symptoms and achieves opioid cessation – or sustained reduced use – in dependent individuals, as measured over 12 months. Ibogaine also provides comparable long-term abstinence in people struggling with other substances.

How is Ibogaine taken?
Ibogaine can be taken in a few forms: some take it by chewing on the shrub’s roots or by swallowing the powder mixed with water. The most common form is Ibogaine hydrochloride salt, which is taken orally.

Where is Ibogaine found?
Ibogaine is a monoterpene indole alkaloid which is found in the root bark of the Tabernanthe Iboga Baill bush in Gabon and West Central Africa. In its raw form it is exported throughout the world, tested and refined, and supplied to treatment providers in Mexico, Central America, Asia, and Europe.

What does Ibogaine do to the body?

Laboratory research on Ibogaine has resulted in reduced cocaine and morphine self-administration in laboratory animals (reviewed in Ref. 6), and has attenuated alcohol intake by alcohol-preferring rats. The compound also reduces the rewarding effects of nicotine in animals. The compound reduces the identical types of craving in humans by restoring and/or repairing dopamine receptors in the brain.
What is the protocol for Ibogaine?

Oral Ibogaine dosing protocol consists of an initial test dose of 2–3 mg/kg of Ibogaine. Depending on response, after ~40 minutes, additional doses of Ibogaine, up to a total of <14 mg/kg, are administered over the course of the treatment session, lasting up to 6 hours.

For how long does Ibogaine last?

Due to profound side effects, Ibogaine is rarely used recreationally, and its potential for addiction is extremely low. Ibogaine lasts much longer than other psychedelics, often having an active window of 24 hours and sometimes even up to 48 hours.  Its therapeutic effect has been measured as lasting approximately 180 days (6 months), which is plenty of time for someone struggling with addiction to form new habits and coping skills, and for pain management patients to acquire alternative resources.

Is Ibogaine treatment effective? A UC Davis study comparing Ibogaine to buprenorphine, one of the most popular drugs used for medication-assisted treatment of OUD, found Ibogaine to be 30% more effective at reducing opioid use while causing fewer side effects.